Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

INTRODUCTION: Increasing evidence support the regulatory role of leptin in osteoarthritis (OA). As high circulating concentrations of leptin disrupt the physiological function of the adipokine in obese individuals, the current study has been undertaken to determine whether the elevated levels of lep...

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Hlavní autoři: Pallu, Stéphane, Francin, Pierre-Jean, Guillaume, Cécile, Gegout-Pottie, Pascale, Netter, Patrick, Mainard, Didier, Terlain, Bernard, Presle, Nathalie
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911905/
https://ncbi.nlm.nih.gov/pubmed/20534145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3048
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