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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis

INTRODUCTION: Increasing evidence support the regulatory role of leptin in osteoarthritis (OA). As high circulating concentrations of leptin disrupt the physiological function of the adipokine in obese individuals, the current study has been undertaken to determine whether the elevated levels of lep...

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Detalhes bibliográficos
Main Authors: Pallu, Stéphane, Francin, Pierre-Jean, Guillaume, Cécile, Gegout-Pottie, Pascale, Netter, Patrick, Mainard, Didier, Terlain, Bernard, Presle, Nathalie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911905/
https://ncbi.nlm.nih.gov/pubmed/20534145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3048
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