Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes

INTRODUCTION: The importance of mechanical signals in normal and inflamed cartilage is well established. Chondrocytes respond to changes in the levels of proinflammatory cytokines and mechanical signals during inflammation. Cytokines like interleukin (IL)-1β suppress homeostatic mechanisms and inhib...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Perera, Priyangi M, Wypasek, Ewa, Madhavan, Shashi, Rath-Deschner, Birgit, Liu, Jie, Nam, Jin, Rath, Bjoern, Huang, Yan, Deschner, James, Piesco, Nicholas, Wu, Chuanyue, Agarwal, Sudha
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911896/
https://ncbi.nlm.nih.gov/pubmed/20509944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3039
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge