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Elevation of osteopontin levels in brain tumor cells reduces burden and promotes survival through the inhibition of cell dispersal

Osteopontin (OPN) is a pleotrophic molecule that has been associated with multiple disorders of the central nervous system (CNS). Its roles in CNS malignancy are unclear but suggest that higher levels of OPN expression correlate with increased tumor grade and increased migratory capacity of tumor ce...

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Detalhes bibliográficos
Main Authors: Selkirk, Stephen M., Morrow, Jay, Barone, Tara A., Hoffer, Alan, Lock, Jeffrey, DeChant, Anne, Mangla, Saisho, Plunkett, Robert J., Miller, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911624/
https://ncbi.nlm.nih.gov/pubmed/17928956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-007-9477-1
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