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Neurite outgrowth from PC12 cells is enhanced by an inhibitor of mechanical channels

GsMTx4, a peptide inhibitor for mechanosensitive ion channels (MSCs), promoted neurite outgrowth from PC12 cells in the presence of NGF in a dose-dependent manner between 5 and 100 μM peptide. Enhanced neurite growth required >12 h of peptide exposure in cells grown with NGF. Adsorption of GsMTx4...

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Detalhes bibliográficos
Main Authors: Gottlieb, Philip A., Barone, Tara, Sachs, Frederick, Plunkett, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922024/
https://ncbi.nlm.nih.gov/pubmed/20600595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.06.066
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