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Apoptosis of oligodendrocytes in the CNS results in rapid focal demyelination

OBJECTIVE: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system that presents with variable pathologies that may reflect different disease-causing mechanisms. Existing animal models of MS induce pathology using either local injection of gliotoxins or stimulation of the im...

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Detalhes bibliográficos
Main Authors: Caprariello, Andrew, Mangla, Saisho, Miller, Robert H., Selkirk, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3464960/
https://ncbi.nlm.nih.gov/pubmed/23034912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23606
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