Synthesis of Macrocyclic Hexaoxazole (6OTD) Dimers, Containing Guanidine and Amine Functionalized Side Chains, and an Evaluation of Their Telomeric G4 Stabilizing Properties

Structure-activity relationship studies were carried out on macrocyclic hexaoxazole (6OTD) dimers, whose core structure stabilizes telomeric G-quadruplexes (G4). Two new 6OTD dimers having side chain amine and guanidine functional groups were synthesized and evaluated for their stabilizing ability a...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Iida, Keisuke, Tera, Masayuki, Hirokawa, Takatsugu, Shin-ya, Kazuo, Nagasawa, Kazuo
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE-Hindawi Access to Research 2010
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911606/
https://ncbi.nlm.nih.gov/pubmed/20700415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/217627
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky