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A Conserved Aspartate Determines Pore Properties of Anion Channels Associated with Excitatory Amino Acid Transporter 4 (EAAT4)

Excitatory amino acid transporter (EAAT) glutamate transporters function not only as secondary active glutamate transporters but also as anion channels. Recently, a conserved aspartic acid (Asp(112)) within the intracellular loop near to the end of transmembrane domain 2 was proposed as a major dete...

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Autors principals: Kovermann, Peter, Machtens, Jan-Philipp, Ewers, David, Fahlke, Christoph
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911312/
https://ncbi.nlm.nih.gov/pubmed/20519505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126557
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