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An amino-terminal point mutation increases EAAT2 anion currents without affecting glutamate transport rates
Excitatory amino acid transporters (EAATs) are prototypical dual function proteins that function as coupled glutamate/Na(+)/H(+)/K(+) transporters and as anion-selective channels. Both transport functions are intimately intertwined at the structural level: Secondary active glutamate transport is bas...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7606670/ https://ncbi.nlm.nih.gov/pubmed/32820048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013704 |
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