Involvement of Inducible 6-Phosphofructo-2-kinase in the Anti-diabetic Effect of Peroxisome Proliferator-activated Receptor γ Activation in Mice

PFKFB3 is the gene that codes for the inducible isoform of 6-phosphofructo-2-kinase (iPFK2), a key regulatory enzyme of glycolysis. As one of the targets of peroxisome proliferator-activated receptor γ (PPARγ), PFKFB3/iPFK2 is up-regulated by thiazolidinediones. In the present study, using PFKFB3/iP...

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Главные авторы: Guo, Xin, Xu, Kefeng, Zhang, Jifeng, Li, Honggui, Zhang, Weiyu, Wang, Huan, Lange, Alex J., Chen, Y. Eugene, Huo, Yuqing, Wu, Chaodong
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2010
Предметы:
Metabolism
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911274/
https://ncbi.nlm.nih.gov/pubmed/20498376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123174
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