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Direct endosomal acidification by the outwardly rectifying CLC-5 Cl(−)/H(+) exchanger
The voltage-gated Cl(−) channel (CLC) family comprises cell surface Cl(−) channels and intracellular Cl(−)/H(+) exchangers. CLCs in organelle membranes are thought to assist acidification by providing a passive chloride conductance that electrically counterbalances H(+) accumulation. Following recen...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2911210/ https://ncbi.nlm.nih.gov/pubmed/20421284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.188540 |
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