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An efficient platform for screening expression and crystallization of glycoproteins produced in human cells

Glycoproteins mediate multiple, diverse and critical cellular functions, that are desirable to explore by structural analysis. However, structure determination of these molecules has been hindered by difficulties expressing milligram quantities of stable, homogeneous protein and in determining, whic...

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Detalhes bibliográficos
Main Authors: Lee, Jeffrey E., Fusco, Marnie L., Saphire, Erica Ollmann
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911120/
https://ncbi.nlm.nih.gov/pubmed/19373230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2009.29
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