Functional Variants in MBL2 Are Associated With Type 2 Diabetes and Pre-Diabetes Traits in Pima Indians and the Old Order Amish

OBJECTIVE: MBL2 encodes the mannose-binding lectin, which is a key player in the innate immune system and has recently been found to play a role in insulin resistance and development of type 1 diabetes and gestational diabetes mellitus. To assess the role of MBL2 in diabetes susceptibility, this gen...

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Autors principals: Muller, Yunhua L., Hanson, Robert L., Bian, Li, Mack, Janel, Shi, Xiaolian, Pakyz, Ruth, Shuldiner, Alan R., Knowler, William C., Bogardus, Clifton, Baier, Leslie J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2010
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911048/
https://ncbi.nlm.nih.gov/pubmed/20522590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1593
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