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Evidence for Novel β-Sheet Structures in Iowa Mutant β-Amyloid Fibrils
Asp23-to-Asn mutation within the coding sequence of β-amyloid, called the Iowa mutation, is associated with early onset, familial Alzheimer’s disease and cerebral amyloid angiopathy, in which patients develop neuritic plaques and massive vascular deposition predominantly of the mutant peptide. We ex...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910621/ https://ncbi.nlm.nih.gov/pubmed/19358576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9002666 |
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