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Copper stabilizes antiparallel β-sheet fibrils of the amyloid β40 (Aβ40)-Iowa variant

Cerebral amyloid angiopathy (CAA) is a vascular disorder that primarily involves deposition of the 40-residue–long β-amyloid peptide (Aβ40) in and along small blood vessels of the brain. CAA is often associated with Alzheimer's disease (AD), which is characterized by amyloid plaques in the brai...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Crooks, Elliot J., Irizarry, Brandon A., Ziliox, Martine, Kawakami, Toru, Victor, Tiffany, Xu, Feng, Hojo, Hironobu, Chiu, Kelley, Simmerling, Carlos, Van Nostrand, William E., Smith, Steven O., Miller, Lisa M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335782/
https://ncbi.nlm.nih.gov/pubmed/32376688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011955
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