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Immunomodulatory Effects of dsRNA and Its Potential as Vaccine Adjuvant
dsRNA can be detected by pattern recognition receptors, for example, TLR3, MDA-5, NLRP3 to induce proinflammatory cytokines responsible for innate/adaptive immunity. Recognized by endosomal TLR3 in myeloid DCs (mDCs), dsRNA can activate mDCs into mature antigen presenting cells (mAPCs) which in turn...
שמור ב:
| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Hindawi Publishing Corporation
2010
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2910503/ https://ncbi.nlm.nih.gov/pubmed/20671921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/690438 |
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