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Protein Kinase Regulated by dsRNA Downregulates the Interferon Production in Dengue Virus- and dsRNA-Stimulated Human Lung Epithelial Cells

BACKGROUND: Dengue virus (DENV) is found in the tropical and subtropical regions and affects millions of people annually. Currently, no specific vaccine or antiviral treatment against dengue virus is available. Innate immunity has been shown to be important for host resistance to DENV infection. Alt...

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Main Authors: Li, Yuye, Xie, Jiong, Wu, Siyu, Xia, Jun, Zhang, Peifen, Liu, Chao, Zhang, Ping, Huang, Xi
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555826/
https://ncbi.nlm.nih.gov/pubmed/23372823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055108
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