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Biogenesis and regulation of insulin-responsive vesicles containing GLUT4

Insulin regulates the trafficking of GLUT4 glucose transporters in fat and muscle cells. In unstimulated cells, GLUT4 is sequestered intracellularly in small, insulin-responsive vesicles. Insulin stimulates the translocation of these vesicles to the cell surface, inserting the transporters into the...

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Autori principali: Bogan, Jonathan S., Kandror, Konstantin V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910140/
https://ncbi.nlm.nih.gov/pubmed/20417083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2010.03.012
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