Linear and conformation specific antibodies in aged beagles after prolonged vaccination with aggregated Abeta

Previously we showed that anti-Aβ peptide immunotherapy significantly attenuated Alzheimer’s-like amyloid deposition in the central nervous system of aged canines. In this report we have characterized the changes that occurred in the humoral immune response over 2.4 years in canines immunized repeat...

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Main Authors: Vasilevko, Vitaly, Pop, Viorela, Kim, Hyun Jin, Saing, Tommy, Glabe, Charles C., Milton, Saskia, Barrett, Edward G., Cotman, Carl W., Cribbs, David H., Head, Elizabeth
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910127/
https://ncbi.nlm.nih.gov/pubmed/20451612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.04.014
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