Ubiquinone Analogs: A Mitochondrial Permeability Transition Pore-Dependent Pathway to Selective Cell Death

BACKGROUND: Prolonged opening of the mitochondrial permeability transition pore (PTP) leads to cell death. Various ubiquinone analogs have been shown to regulate PTP opening but the outcome of PTP regulation by ubiquinone analogs on cell fate has not been studied yet. METHODOLOGY/PRINCIPAL FINDINGS:...

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Detalhes bibliográficos
Main Authors: Devun, Flavien, Walter, Ludivine, Belliere, Julie, Cottet-Rousselle, Cécile, Leverve, Xavier, Fontaine, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909912/
https://ncbi.nlm.nih.gov/pubmed/20668684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011792
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