Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

Metformin, a drug widely used in the treatment of Type II diabetes, has recently received attention owing to new findings regarding its mitochondrial and cellular effects. In the present study, the effects of metformin on respiration, complex 1 activity, mitochondrial permeability transition, cytoch...

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Bibliographic Details
Main Authors: Guigas, Bruno, Detaille, Dominique, Chauvin, Christiane, Batandier, Cécile, De OLIVEIRA, Frédéric, Fontaine, Eric, Leverve, Xavier
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2004
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133963/
https://ncbi.nlm.nih.gov/pubmed/15175014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040885
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