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Metformin inhibits mitochondrial permeability transition and cell death: a pharmacological in vitro study

Metformin, a drug widely used in the treatment of Type II diabetes, has recently received attention owing to new findings regarding its mitochondrial and cellular effects. In the present study, the effects of metformin on respiration, complex 1 activity, mitochondrial permeability transition, cytoch...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Guigas, Bruno, Detaille, Dominique, Chauvin, Christiane, Batandier, Cécile, De OLIVEIRA, Frédéric, Fontaine, Eric, Leverve, Xavier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1133963/
https://ncbi.nlm.nih.gov/pubmed/15175014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040885
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