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K(Ca) Channels as Therapeutic Targets in Episodic Ataxia Type-2
Episodic ataxia type-2 (EA2) is an inherited movement disorder caused by mutations in the gene encoding the Ca(v)2.1α1 subunit of the P/Q-type voltage-gated calcium channel that result in an overall reduction in the P/Q-type calcium current. A consequence of these mutations is loss of precision of p...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909841/ https://ncbi.nlm.nih.gov/pubmed/20505091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6341-09.2010 |
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