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K(Ca) Channels as Therapeutic Targets in Episodic Ataxia Type-2

Episodic ataxia type-2 (EA2) is an inherited movement disorder caused by mutations in the gene encoding the Ca(v)2.1α1 subunit of the P/Q-type voltage-gated calcium channel that result in an overall reduction in the P/Q-type calcium current. A consequence of these mutations is loss of precision of p...

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Autori principali: Alviña, Karina, Khodakhah, Kamran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909841/
https://ncbi.nlm.nih.gov/pubmed/20505091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6341-09.2010
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