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Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers

AIM: To determine the pharmacokinetics, pharmacodynamics, safety and tolerability of multiple oral doses of ticagrelor, a P2Y(12) receptor antagonist, in healthy volunteers. METHODS: This was a randomized, single-blind, placebo-controlled, ascending dose study. Thirty-two subjects received ticagrelo...

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Sonraí Bibleagrafaíochta
Main Authors: Butler, Kathleen, Teng, Renli
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909809/
https://ncbi.nlm.nih.gov/pubmed/20642549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03669.x
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