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Finding Biomarker Signatures in Pooled Sample Designs: A Simulation Framework for Methodological Comparisons

Detection of discriminating patterns in gene expression data can be accomplished by using various methods of statistical learning. It has been proposed that sample pooling in this context would have negative effects; however, pooling cannot always be avoided. We propose a simulation framework to exp...

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Detaylı Bibliyografya
Asıl Yazarlar: Telaar, Anna, Nürnberg, Gerd, Repsilber, Dirk
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909718/
https://ncbi.nlm.nih.gov/pubmed/20671968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/318573
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