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Biomarker discovery in heterogeneous tissue samples -taking the in-silico deconfounding approach
BACKGROUND: For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved. Conclusions have to rely on estimation of gene expression signals for homogeneous cell populations, e.g. by applying micro-dissection, fluorescence act...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098067/ https://ncbi.nlm.nih.gov/pubmed/20070912 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-27 |
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