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Transcription-dependent mobilization of nucleosomes at accessible T cell receptor gene segments in vivo

Accessibility of chromosomal recombination signal sequences to the RAG protein complex is known to be essential for V(D)J recombination at antigen receptor loci in vivo. Previous studies have addressed the roles of cis-acting regulatory elements and germline transcription in the covalent modificatio...

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Main Authors: Kondilis-Mangum, Hrisavgi D., Cobb, Robin Milley, Osipovich, Oleg, Srivatsan, Sruti, Oltz, Eugene M., Krangel, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909652/
https://ncbi.nlm.nih.gov/pubmed/20483751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903923
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