Target Dependent B7-H1 Regulation Contributes to Clearance of CNS Infection and Dampens Morbidity

The neurotropic coronavirus JHMV persists in oligodendroglia despite the presence of virus-specific CD8 T cells. Expression of programmed death-1 (PD-1) and B7-H1 were studied during acute and persistent infection to examine if this negative regulatory mechanism contributes to CNS viral persistence....

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Detalhes bibliográficos
Main Authors: Phares, Timothy W., Ramakrishna, Chandran, Parra, Gabriel I., Epstein, Alan, Chen, Lieping, Atkinson, Roscoe, Stohlman, Stephen A., Bergmann, Cornelia C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909606/
https://ncbi.nlm.nih.gov/pubmed/19380790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803557
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