Inhibition of Interferon-γ Signaling in Oligodendroglia Delays Coronavirus Clearance without Altering Demyelination

Infection of the central nervous system (CNS) by the neurotropic JHM strain of mouse hepatitis virus (JHMV) induces an acute encephalomyelitis associated with demyelination. To examine the anti-viral and/or regulatory role of interferon-γ (IFN-γ) signaling in the cell that synthesizes and maintains...

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Detalhes bibliográficos
Main Authors: González, John M., Bergmann, Cornelia C., Ramakrishna, Chandran, Hinton, David R., Atkinson, Roscoe, Hoskin, Jason, Macklin, Wendy B., Stohlman, Stephen A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606538/
https://ncbi.nlm.nih.gov/pubmed/16507895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050496
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