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Predicting genetic modifier loci using functional gene networks
Most phenotypes are genetically complex, with contributions from mutations in many different genes. Mutations in more than one gene can combine synergistically to cause phenotypic change, and systematic studies in model organisms show that these genetic interactions are pervasive. However, in human...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909577/ https://ncbi.nlm.nih.gov/pubmed/20538624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.102749.109 |
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