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Predicting genetic modifier loci using functional gene networks
Most phenotypes are genetically complex, with contributions from mutations in many different genes. Mutations in more than one gene can combine synergistically to cause phenotypic change, and systematic studies in model organisms show that these genetic interactions are pervasive. However, in human...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909577/ https://ncbi.nlm.nih.gov/pubmed/20538624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.102749.109 |
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