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β–Catenin expression in the bone marrow microenvironment is required for long-term maintenance of primitive hematopoietic cells

Hematopoiesis is dependent upon the bone marrow microenvironment, which is comprised of multiple mesenchymal cell types, including fibroblasts, endothelial cells, osteoblasts and stroma progenitors. The canonical Wnt signaling pathway, which relies on the β-catenin protein to mediate its signal, is...

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Detalhes bibliográficos
Main Authors: Nemeth, Michael J., Mak, Kinglun Kingston, Yang, Yingzi, Bodine, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909544/
https://ncbi.nlm.nih.gov/pubmed/19415781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.32
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