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Interleukin-10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice

In atherogenesis, macrophage foam cell formation is modulated by pathways involving both the uptake and efflux of cholesterol. We recently showed that interleukin-10 (IL-10) modulates lipid metabolism by enhancing both uptake and efflux of cholesterol in macrophages. However, the mechanistic details...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Han, Xinbing, Kitamoto, Shiro, Wang, Hongwei, Boisvert, William A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Federation of American Societies for Experimental Biology 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909283/
https://ncbi.nlm.nih.gov/pubmed/20354139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-148155
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