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Interleukin-10 overexpression in macrophages suppresses atherosclerosis in hyperlipidemic mice
In atherogenesis, macrophage foam cell formation is modulated by pathways involving both the uptake and efflux of cholesterol. We recently showed that interleukin-10 (IL-10) modulates lipid metabolism by enhancing both uptake and efflux of cholesterol in macrophages. However, the mechanistic details...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Federation of American Societies for Experimental Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909283/ https://ncbi.nlm.nih.gov/pubmed/20354139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-148155 |
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