Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation

OBJECTIVE: To investigate whether apocynin protects the diaphragm from wasting and oxidative stress during mechanical ventilation (MV). DESIGN: Prospective, randomized, controlled study. SETTING: Research laboratory. SUBJECTS: Adult female Sprague-Dawley rats. INTERVENTIONS: Rats were randomly assig...

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Autors principals: McClung, Joseph M., Van Gammeren, Darin, Whidden, Melissa A., Falk, Darin J., Kavazis, Andreas N., Hudson, Matt B., Gayan-Ramirez, Ghislaine, Decramer, Marc, DeRuisseau, Keith C., Powers, Scott K.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909189/
https://ncbi.nlm.nih.gov/pubmed/19242334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0b013e31819cef63
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