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Monotonicity, frustration, and ordered response: an analysis of the energy landscape of perturbed large-scale biological networks
BACKGROUND: For large-scale biological networks represented as signed graphs, the index of frustration measures how far a network is from a monotone system, i.e., how incoherently the system responds to perturbations. RESULTS: In this paper we find that the frustration is systematically lower in tra...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2909160/ https://ncbi.nlm.nih.gov/pubmed/20537143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-4-83 |
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