A Novel Type I Interferon-producing Cell Subset in Murine Lupus

Excess type-I interferons (IFN-I) have been linked to the pathogenesis of systemic lupus erythematosus (SLE). Therapeutic use of IFN-I can trigger the onset of SLE and most lupus patients display upregulation of a group of interferon stimulated genes (ISGs). While this “interferon signature” has bee...

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Autors principals: Lee, Pui Y., Weinstein, Jason S., Nacionales, Dina C., Scumpia, Philip O., Li, Yi, Butfiloski, Edward, van Rooijen, Nico, Moldawer, Lyle, Satoh, Minoru, Reeves, Westley H.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909121/
https://ncbi.nlm.nih.gov/pubmed/18354236
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