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B Cell Proliferation, Somatic Hypermutation, Class Switch Recombination, and Autoantibody Production in Ectopic Lymphoid Tissue in Murine Lupus
Intraperitoneal exposure of non-autoimmune mice to tetramethylpentadecane (TMPD) causes lupus and the formation of ectopic lymphoid tissue. Although associated with humoral autoimmunity, it is not known whether antibody responses develop within ectopic lymphoid tissue or if B cells only secondarily...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3395367/ https://ncbi.nlm.nih.gov/pubmed/19299721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800771 |
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