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B Cell Proliferation, Somatic Hypermutation, Class Switch Recombination, and Autoantibody Production in Ectopic Lymphoid Tissue in Murine Lupus

Intraperitoneal exposure of non-autoimmune mice to tetramethylpentadecane (TMPD) causes lupus and the formation of ectopic lymphoid tissue. Although associated with humoral autoimmunity, it is not known whether antibody responses develop within ectopic lymphoid tissue or if B cells only secondarily...

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書誌詳細
主要な著者: Nacionales, Dina C., Weinstein, Jason S., Yan, Xiao-Jie, Albesiano, Emilia, Lee, Pui Y., Kelly-Scumpia, Kindra M., Lyons, Robert, Satoh, Minoru, Chiorazzi, Nicholas, Reeves, Westley H.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3395367/
https://ncbi.nlm.nih.gov/pubmed/19299721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0800771
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