DEFICIENCY OF THE TYPE I INTERFERON RECEPTOR PROTECTS MICE FROM EXPERIMENTAL LUPUS

OBJECTIVE: Systemic lupus erythematosus (SLE) is diagnosed by a spectrum of clinical manifestations and autoantibodies associated with abnormal expression of Type I interferon (IFN-I) stimulated genes (ISGs). The role of IFN-I in the pathogenesis of SLE remains uncertain, partly due to the lack of s...

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Autori principali: Nacionales, Dina C., Kelly-Scumpia, Kindra M., Lee, Pui Y., Weinstein, Jason S., Lyons, Robert, Sobel, Eric, Satoh, Minoru, Reeves, Westley H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2909118/
https://ncbi.nlm.nih.gov/pubmed/17968932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23023
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