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ACCELERATED LIVER REGENERATION AND HEPATOCARCINOGENESIS IN MICE OVEREXPRESSING SERINE-45 MUTANT BETA-CATENIN

The Wnt/β-catenin pathway is implicated in the pathogenesis of hepatocellular cancer (HCC). We have developed a transgenic mouse (TG) in FVB strain that overexpresses Ser45-mutated-β-catenin in hepatocytes to study the effects on liver regeneration and cancer. In the two independent TG lines, adult...

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書誌詳細
主要な著者: Nejak-Bowen, Kari N, Thompson, Michael D., Singh, Sucha, Bowen, William C., Dar, Mohd Jamal, Khillan, Jaspal, Dai, Chunsun, Monga, Satdarshan P S
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908905/
https://ncbi.nlm.nih.gov/pubmed/20432254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23538
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