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ACCELERATED LIVER REGENERATION AND HEPATOCARCINOGENESIS IN MICE OVEREXPRESSING SERINE-45 MUTANT BETA-CATENIN
The Wnt/β-catenin pathway is implicated in the pathogenesis of hepatocellular cancer (HCC). We have developed a transgenic mouse (TG) in FVB strain that overexpresses Ser45-mutated-β-catenin in hepatocytes to study the effects on liver regeneration and cancer. In the two independent TG lines, adult...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908905/ https://ncbi.nlm.nih.gov/pubmed/20432254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23538 |
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