ACCELERATED LIVER REGENERATION AND HEPATOCARCINOGENESIS IN MICE OVEREXPRESSING SERINE-45 MUTANT BETA-CATENIN

The Wnt/β-catenin pathway is implicated in the pathogenesis of hepatocellular cancer (HCC). We have developed a transgenic mouse (TG) in FVB strain that overexpresses Ser45-mutated-β-catenin in hepatocytes to study the effects on liver regeneration and cancer. In the two independent TG lines, adult...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Nejak-Bowen, Kari N, Thompson, Michael D., Singh, Sucha, Bowen, William C., Dar, Mohd Jamal, Khillan, Jaspal, Dai, Chunsun, Monga, Satdarshan P S
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908905/
https://ncbi.nlm.nih.gov/pubmed/20432254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23538
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados