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Molecular Determinants of Substrate Specificity in Plant 5′-Methylthioadenosine Nucleosidases

5′-Methylthioadenosine (MTA)/S-adenosylhomocysteine (SAH) nucleosidase (MTAN) is essential for cellular metabolism and development in many bacterial species. While the enzyme is found in plants, plant MTANs appear to select for MTA preferentially, with little or no affinity for SAH. To understand wh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Siu, Karen K. W., Lee, Jeffrey E., Sufrin, Janice R., Moffatt, Barbara A., McMillan, Martin, Cornell, Kenneth A., Isom, Chelsea, Howell, P. Lynne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908701/
https://ncbi.nlm.nih.gov/pubmed/18342331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.088
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