Molecular Determinants of Substrate Specificity in Plant 5′-Methylthioadenosine Nucleosidases

5′-Methylthioadenosine (MTA)/S-adenosylhomocysteine (SAH) nucleosidase (MTAN) is essential for cellular metabolism and development in many bacterial species. While the enzyme is found in plants, plant MTANs appear to select for MTA preferentially, with little or no affinity for SAH. To understand wh...

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Bibliografiske detaljer
Main Authors: Siu, Karen K. W., Lee, Jeffrey E., Sufrin, Janice R., Moffatt, Barbara A., McMillan, Martin, Cornell, Kenneth A., Isom, Chelsea, Howell, P. Lynne
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908701/
https://ncbi.nlm.nih.gov/pubmed/18342331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.088
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