Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis

BACKGROUND: Chronic Lymphocytic Leukemia (CLL) pathogenesis has been linked to the prolonged survival and/or apoptotic resistance of leukemic B cells in vivo, and is thought to be due to enhanced survival signaling responses to environmental factors that protect CLL cells from spontaneous and chemot...

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Bibliographic Details
Main Authors: O'Hayre, Morgan, Salanga, Catherina L., Kipps, Thomas J., Messmer, Davorka, Dorrestein, Pieter C., Handel, Tracy M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908618/
https://ncbi.nlm.nih.gov/pubmed/20661426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011716
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