Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers

BACKGROUND: The tumor suppressor pRb plays a key role regulating cell cycle arrest, and disturbances in the RB1 gene have been reported in different cancer forms. However, the literature reports contradictory findings with respect to a pro - versus anti - apoptotic role of pRb, and the consequence o...

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Bibliografiska uppgifter
Huvudupphovsmän: Berge, Elisabet Ognedal, Knappskog, Stian, Geisler, Stephanie, Staalesen, Vidar, Pacal, Marec, Børresen-Dale, Anne-Lise, Puntervoll, Pål, Lillehaug, Johan Richard, Lønning, Per Eystein
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908580/
https://ncbi.nlm.nih.gov/pubmed/20594292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-173
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