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Dasatinib impairs long-term expansion of leukemic progenitors in a subset of acute myeloid leukemia cases

A number of signaling pathways might be frequently disrupted in acute myeloid leukemia (AML). We questioned whether the dual SRC/ABL kinase inhibitor dasatinib can affect AML cells and whether differences can be observed with normal CD34(+) cells. First, we demonstrated that normal cord blood (CB) C...

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Bibliografski detalji
Glavni autori: Han, Lina, Schuringa, Jan Jacob, Mulder, André, Vellenga, Edo
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908401/
https://ncbi.nlm.nih.gov/pubmed/20387067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00277-010-0948-7
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