Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2

Leukemic stem cells (LSCs) reside within bone marrow niches that maintain their relatively quiescent state and convey resistance to conventional treatment. Many of the microenvironmental signals converge on RAC GTPases. Although it has become clear that RAC proteins fulfill important roles in the he...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Capala, Marta E., Maat, Henny, Bonardi, Francesco, van den Boom, Vincent, Kuipers, Jeroen, Vellenga, Edo, Giepmans, Ben N. G., Schuringa, Jan Jacob
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446344/
https://ncbi.nlm.nih.gov/pubmed/26016997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128585
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky