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Population differences in platinum toxicity as a means to identify novel genetic susceptibility variants

OBJECTIVES: Clinical studies show that Asians (ASN) are more susceptible to toxicities associated with platinum-containing regimens. We hypothesized that studying ASN as an `enriched phenotype' population could enable the discovery of novel genetic determinants of platinum susceptibility. METHO...

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Détails bibliographiques
Auteurs principaux: O'Donnell, Peter H., Gamazon, Eric, Zhang, Wei, Stark, Amy L., Kistner-Griffin, Emily O., Huang, R. Stephanie, Dolan, M. Eileen
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908307/
https://ncbi.nlm.nih.gov/pubmed/20393316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e3283396c4e
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