Calpain-mediated down-regulation of myelin-associated glycoprotein in lysophosphatidic acid-induced neuropathic pain

Lysophosphatidic acid receptor (LPA(1)) signaling initiates neuropathic pain through demyelination of the dorsal root (DR). Although LPA is found to cause down-regulation of myelin proteins underlying demyelination, the detailed mechanism remains to be determined. In the present study, we found that...

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Bibliographic Details
Main Authors: Xie, Weijiao, Uchida, Hitoshi, Nagai, Jun, Ueda, Mutsumi, Chun, Jerold, Ueda, Hiroshi
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908211/
https://ncbi.nlm.nih.gov/pubmed/20420580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06664.x
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