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Platelets mediate cytotoxic T lymphocyte–induced liver damage
We found that platelet depletion reduces intrahepatic accumulation of virus-specific cytotoxic T lymphocytes (CTLs) and organ damage in mouse models of acute viral hepatitis. Transfusion of normal but not activation-blocked platelets in platelet-depleted mice restored accumulation of CTLs and severi...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908083/ https://ncbi.nlm.nih.gov/pubmed/16258538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1317 |
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