Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

Using transgenic mice that replicate hepatitis B virus (HBV) in their livers, we previously showed that passively transferred HBV-specific cytotoxic T cells (CTLs) recruit antigen-nonspecific lymphomononuclear and polymorphonuclear inflammatory cells that contribute to the pathogenesis of liver dise...

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Autori principali: Sitia, Giovanni, Isogawa, Masanori, Kakimi, Kazuhiro, Wieland, Stefan F., Chisari, Francis V., Guidotti, Luca G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129753/
https://ncbi.nlm.nih.gov/pubmed/12368481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.172521999
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