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Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes

Using transgenic mice that replicate hepatitis B virus (HBV) in their livers, we previously showed that passively transferred HBV-specific cytotoxic T cells (CTLs) recruit antigen-nonspecific lymphomononuclear and polymorphonuclear inflammatory cells that contribute to the pathogenesis of liver dise...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Sitia, Giovanni, Isogawa, Masanori, Kakimi, Kazuhiro, Wieland, Stefan F., Chisari, Francis V., Guidotti, Luca G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2002
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368481/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.172521999
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